BACKGROUND Many authors have claimed that hyperthyroidism protects against thyroid cancer and believed that the incidence of malignancy is lower in patients with toxic multinodular goiter (TMG) than in those with non-toxic multinodular goiter. But in recent studies, it was reported that the incidence of malignancy with TMG is not as low as previously thought. AIM To compare the thyroid cancer...

The RAS protooncogene has an important, although not yet established role in thyroid neoplasia. In this study, we evaluated the H-RAS mRNA and protein levels in human samples of nontoxic and toxic multinodular goiter samples, according to serum TSH levels. The mean of H-RAS mRNA levels in nodules of nontoxic nodular goiter were significantly increased compared to nonnodular tissue (1.49+/-1.21 ...

Aim: To compare patients with toxic and non-toxic nodular/multinodular goiter in terms of clinical, sonographical cytological features.
 Material Method: The medical data 326 were reviewed retrospectively. Clinical sonographic features examined. Four hundred eighty-one nodules compared sonographically cytologically. One twenty-four had nodular 202 them goiter.
 Results: group was olde...

3 Bourdoux PP, Ermans AM, Mukalay wa Mukalay A, Filetti S, Vigerni R. Iodine-induced thyrotoxicosis in Kivu, Zaire. Lancet 1996; 347: 552–53. 4 Baltisberger BL, Minder ChE, Bürgi H. Decrease of incidence of toxic nodular goitre in a region of Switzerland after full correction of mild iodine deficiency. Eur J Endocrinol 1995; 132: 546–49. 5 Corvilain B, van Sande J, Dumont JE, Bourdoux P, Ermans...

BACKGROUND Some of the thyroid disorders (TD) and Myasthenia gravis (MG) are autoimmune related disease. The purpose of the study to evaluate the relationship of MG with all morphological and functional thyroid disorders. METHODS We constructed a population-based cohort study during the period from January 2000-December 2002 by using reimbursement data from the Bureau National Health Insuranc...